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Index of (In)Famous Research

WARNING: some of these links lead to graphic upsetting material.

The Tuskegee Study

Bad Blood: The Troubling Legacy of the Tuskegee Syphilis Study. University of Virginia Health Sciences Library, Historical Collections. 2004-06-23. Available from (External) http://www.med.virginia.edu/hs-library/historical/apology/index.html . Accessibility verified on 2006-05-07.

Rivers E, Schuman SH, Simpson L, Olansky S. Twenty Years of Followup Experience in a Long-Range Medical Study. Public Health Reports. 1953;68(4):391-395. Available from (External) http://www.gpc.edu/~shale/humanities/composition/assignments/experiment/rivers.html . Accessibility verified on 2006-05-07.

Center for Disease Control (CDC) Tuskegee Syphilis Study Page. 2005-11-17. Available from (External) http://www.cdc.gov/nchstp/od/tuskegee/index.html . Accessibility verified on 2006-05-07.

National Library of Medicine Finding Aid to the Documents on the Origin and Development of the Tuskegee Syphilis Study, 1921-1973. 2004. Available from (External) http://www.nlm.nih.gov/hmd/manuscripts/ead/tuskegee264.html . Accessibility verified on 2006-05-07.

The Tuskegee Syphilis Study Internet Resources. Available from (External) http://www.gpc.edu/~shale/humanities/composition/assignments/experiment/tuskegee.html . Accessibility verified on 2006-05-07. (Courtesy of Professor Steven Hale, Georgia Perimeter College.)

The Nazis

The text of the indictment that began the trials at Nuremberg is preserved at the United States Holocaust Museum:

The Doctors Trial, The Medical Case of the Subsequent Nuremberg Proceedings, from the official trial record: Trials of War Criminals before the Nuremberg Military Tribunals under Control Council Law No. 10. Nuremberg, October 1946 – April 1949, Washington, D.C.: U.S. G.P.O, 1949 – 1953. Available from (External) http://www.ushmm.org/research/doctors/indiptx.htm . Accessibility verified on 2006-05-07.

The Doctors Trial: The Medical Case of the Subsequent Nuremberg Proceedings. United States Holocaust Museum. Undated. Available from (External) http://www.ushmm.org/research/doctors/ . Accessibility verified on 2006-05-07.

Nuremberg Trials Project A Digital Document Collection — Harvard Law School Library. July, 2003. Available from (External) http://nuremberg.law.harvard.edu/php/docs_swi.php?DI=1&text=overview . Accessibility verified on 2006-05-07.

Nazi Research in World War II. Medical Experiments I: Mass Sterilization; Medical Experiments II: Freezing, Low Pressure And Others. Undated. Available from (External) http://facultystaff.vwc.edu/~dgraf/nazidocs.txt . Accessibility verified on 2006-05-07. (Courtesy of Professor Daniel Graf, Department of History, Virginia Wesleyan University.)

Porton Downs

Historical Survey of the Porton Down Service Volunteer Programme 1939-1989. Ministry of Defense. June, 2006. Available from (External) http://www.mod.uk/DefenceInternet/AboutDefence/Issues/HistoricalSurveyOfThePortonDownServceVounteerProgramme19391989.htm . Accessibility verified on 2006-07-15.

Albert Kligman M.D. and Dermatology Research at Holmslberg Prison

Goldfarb NM. Ackerman on Kligman: A Shameful Story in American Clinical Research. Journal of Clinical Research Best Practices. 2006;2(4). Available from (External) http://www.firstclinical.com/resources/journal/0604/Ackerman.pdf . Accessibility verified on 2006-05-07.

Hornblum AM. Acres of Skin. 1998. In: Journal of Clinical Research Best Practices. 2006;2(4). Available from (External) http://www.firstclinical.com/resources/journal/0604/Acres.pdf . Accessibility verified on 2006-05-07.

Other Cases

[Pfizer's Trovan] Nigerian Federal Ministry of Health Report. The Washington Post web site. Accessed on 2006-10-19 at: (External) http://www.washingtonpost.com/wp-srv/world/documents/Clinical_Trial_Report.pdf

Panel Faults Pfizer in '96 Clinical Trial In Nigeria. Joe Stephens. The Washington Post. 2006-05-06. Accessed on 2006-10-19 at: (External) http://www.washingtonpost.com/wp-dyn/content/article/2006/05/06/AR2006050601338.html

Related Information on the CIRCARE Web Site

TGN1412 Tegenero AG Clinical Trial

Ketek™ / Clinical Trials and FDA Approval

SFBC International Inc.

Research on Induced Malaria for HIV / Henry Heimlich M.D. and The Heimlich Institute Foundation

Research on Induced Malaria for Lyme Disease / Henry Heimlich M.D. and The Heimlich Institute Foundation

Use of Unapproved Medical Devices at A. I. Dupont Hospital for Children / William I. Norwood M.D. and Colleagues and the Cheatham Covered Platinum Stent

The Great Lakes College of Clinical Medicine Institutional Review Board

EmpowerPlus Research / University of Calgary, University of Utah, The Synergy Group of Canada Inc., and Truehope Nutritional Support Ltd.

Pesticide Research in Human Subjects

Jesse Gelsinger and Gene Transfer Research for Ornithine Transcarbamylase Deficiency at The Institute for Human Gene Therapy, The University of Pennsylvania

See also:

Legal Cases, Opinions, New and Pending Litigation in Human Research Protections

State Medical Board Orders / Human Research Protections and Related Issues

Form FDA 483s Notices of Inspectional Findings

News Stories on Human Research Protections / 2001 and Earlier

FDA Warning Letters Organized by CIRCARE:

FDA Warning Letters to Institutional Review Boards (IRBs)

FDA Warning Letters to Clinical Investigators (A – E)

FDA Warning Letters to Clinical Investigators (F – L)

FDA Warning Letters to Clinical Investigators (M – R)

FDA Warning Letters to Clinical Investigators (S – Z)

FDA Warning Letters to Sponsors and Contract Research Organizations (CROs)

Additional Resources


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Last Updated: 2007-04-01

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